133493 - HPV Vaccines: The Next Generation
- : Online
A Category 2, 1 hour online case study based program on HPV VaccinesRelevance to General Practice
Human papillomaviruses (HPVs) infect and replicate mainly within cutaneous and mucosal epithelial tissues. Approximately 40 HPV types infect the anogenital tract.
“High-risk” (HR) or oncogenic HPV types, including types 16, 18, 31, 33, 35, 45, 52 and 58, are associated with the development of cancer. The majority of genital HPV infections are subclinical and resolve spontaneously within a 12 to 24 months. However, approximately 3% to 10% of HR-HPV infections persist resulting in cellular abnormalities, such as cervical intraepithelial neoplasia (CIN), that may eventually progress into cancer. Cervical cancer usually occurs 10 to 20 years after initial infection with HR-HPV types.
HPV types 6 and 11, designated “low-risk” (LR), cause about 95% of genital warts and all cases of recurrent respiratory papillomatosis.