ICU learning pathway | Acid base balance and buffers
Acid Base Balance and Buffers
Session overview
Description
An account of acid-base physiology and its relevance to anaesthesia.
By the end of this session you will be able to:
- Describe the chemistry of acids, bases and hydrogen ions
- Explain the pH scale and hydrogen ion concentration
- State the role of buffers
- State physiological compensatory mechanisms
- Describe the principal mechanisms that control hydrogen ion concentration
- Describe the newer physicochemical theories of hydrogen ion control
- Identify the common disorders of hydrogen ion balance
Anaesthetists are able to influence the acid-base status when providing anaesthetic care. Manipulation of normal physiology, drugs and coexisting acid-base abnormality may all contribute to outcome.
An understanding of the processes that influence normal acid-base physiology, together with abnormalities is essential to ensure safe delivery of care.
This session will review basic physiology and build knowledge of more complex physicochemical processes, that explain disorders of acid-base physiology.
- Anaesthesia | Pharmacology | Pharmacokinetics prin...
- Posted By eIntegrity Healthcare e-Learning
- Posted Date: 2026-05-19
- Location:Online
- This session explains the variations in pharmacokinetics as observed in different anaesthetic patient populations.
- Anaesthesia | Pharmacology | Target controlled inf...
- Posted By eIntegrity Healthcare e-Learning
- Posted Date: 2026-05-19
- Location:Online
- This session will develop the three compartment model to include an effect-site and discuss its application to target-controlled infusions used for induction and maintenance of anaesthesia. The concept of context-sensitive half-time will be introduced.
- Anaesthesia | Pharmacology | Clearance and volume ...
- Posted By eIntegrity Healthcare e-Learning
- Posted Date: 2026-05-19
- Location:Online
- This session will discuss clearance and volume of distribution and methods used to estimate and measure these kinetic parameters.
- Anaesthesia | Pharmacology | Two- and three-compar...
- Posted By eIntegrity Healthcare e-Learning
- Posted Date: 2026-05-19
- Location:Online
- This session will develop pharmacokinetic modelling. The two- and three-compartment models will be introduced showing how the parameters described in a simple model are used in these more complicated models.
- Anaesthesia | Pharmacology | Introduction to pharm...
- Posted By eIntegrity Healthcare e-Learning
- Posted Date: 2026-05-19
- Location:Online
- This session will introduce pharmacokinetics and modelling. The simple one-compartment model will be described and reasons presented as to why such a model rarely describes drug behaviour.