Acute Medicine | Biochemistry | Strong ion theory

Strong Ion Theory
Session Overview
Description
A brief overview of strong ion theory, particularly relating to metabolic acidosis.

Learning Objectives

By the end of this session you will be able to:

• State the determinants of pH according to the strong ion theory

The traditional theory for understanding acid-base balance within humans, both in health and disease, is based upon the Henderson-Hasselbalch equation, derived in 1916.

In 1981, Peter Stewart published an alternative theory, the strong ion theory, based on the law of electrochemical neutrality [1].

This session discusses both theories