New UTI Vaccine Is Pineapple-Flavoured, Oral-Based, And May Prevent Recurring UTIs For Up To 9 Years
A pineapple-flavoured UTI vaccine could prevent recurrent urinary tract infections (UTIs) and fight treatment-resistant bacteria. However, it has ...
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New UTI Vaccine Is Pineapple-Flavoured, Oral-Based, And May Prevent Recurring UTIs For Up To 9 Years
A pineapple-flavoured UTI vaccine could prevent recurrent urinary tract infections (UTIs) and fight treatment-resistant bacteria. However, it has yet to be cleared of widespread usage in Australia, the US, and the UK.
The MV140 vaccine can alleviate the risk of antibiotic resistance in UTIs treated with commonly used antibiotics. The vaccine is orally applied under the tongue, where the stimulus to the oropharyngeal system can trigger a strong immune response in the bladder. Various studies on MV140 have demonstrated its potential benefits to respondents with recurrent UTIs. In 2022, women who received the vaccine only had zero to one instance of UTIs in nine months.
Meanwhile, recent results from a long-term study revealed that 54% of their participants (72 women and 17 men) remained UTI-free for nine years, while the remainder only had fewer and less severe symptoms. Experts suggest that MV140 should now be tested on more complex populations, such as chronic UTIs, children, and immunocompromised individuals.
As of writing, MV140 has yet to be approved in most countries, and there is yet to be an application for the vaccine in Australia’s Therapeutic Goods Administration. However, doctors in Australia can apply to prescribe it to specific patients via the special access scheme or to become an authorised prescriber to multiple patients. The MV140 vaccine is another potential solution, among others such as a rapid-dissolving tablet and a directly-administered cellular vaccine, that also aims to alleviate UTI symptoms without resorting to antibiotic treatments.
Urinary tract infections are among the most common bacterial infections, with more than 50% of women and 20% of men having a UTI at some point in their lifespan. Recurring instances of the infection may also occur in patients, with symptoms appearing at least two times in six months or at least three times in a year.
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