Dental local anaesthetic agents course for Dental Practitioners



This session describes the common structure of injectable local anaesthetics (LAs) along with their action on neurotransmission. It also discusses the effect the body has on LAs, from administration to excretion. The use of vasoconstrictors in dental LAs will be considered.
Learning objectives
By the end of this session you will be able to:
- describe the common core structure of injectable local anaesthetic agents
- describe the fundamentals of neurotransmission and the effects of local anaesthetic on neurotransmission
- relate physiological conditions to local anaesthetic pharmacokinetics
- describe how local anaesthetic agents are absorbed, distributed, metabolised and excreted
- list and describe the vasoconstrictors used in dental local anaesthetic agents
This session provides an overview of the chemical structure of injectable local anaesthetic agents.
Before commencing this session you should have knowledge of:
- cell membrane structure and basic physiology
- common chemical nomenclature
- common mechanisms of drug metabolism
- basic neurotransmission
- basic physiology of neurotransmitter sites and actions
Hannah is a Speciality Doctor in Oral Surgery at Newcastle Dental Hospital.


Dr Kathy Wilson is an Associate Specialist in Dental Sedation at Newcastle Dental Hospital.
Currently lecturing in the field of dental sedation and special care dentistry at undergraduate and postgraduate level, Kathy has extensive clinical experience in management of the anxious dental patient.
Kathy is also part of the Module Editorial Team at e-Den, and is Module Editor for Module 3 Anxiety and Pain Control in Dentistry.
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